Rapidly lowering brain temperature can reduce the incidence and severity of intracranial edema as well as mortality and complications during treatment and recovery from traumatic brain injury. Few options for targeted brain cooling are currently on the market and none of these technologies are particularly well suited for military implementation. To fill this gap, Vivonics is developing ICEPICC (Intranasal Cooler for Encephalopathy Prevention In Combat Casualties), an intranasal cooling system based on forced cold-air convection, which is simple and well suited to the military environment because it is easily operated and supported in a wide range of settings and has shown to provide effective cooling. The portable and easily supported ICEPICC design will enable military use of prophylactic and therapeutic cooling soon after brain injury.
Miniature Integrated Circuits Reporting Overall Status (MICROS) provides sophisticated monitoring and analysis of physiologic, and potentially cognitive status, data in a wearable patch format with integrated power harvesting to achieve long operating time without replacement or recharging. MICROS will initially be used for continuous physiological monitoring of military troops during vigorous training, promoting effective training results at reduced risk of harm from over exertion. Future applications include monitoring deployed troops and combat casualties. Integrated circuit design of critical sections was successfully evaluated, while a prototype is currently being developed and tested. Vivonics, a medical technology development company improving human health and performance, is seeking to connect with DOD program offices for technology transition and with strategic partners and investors for scale-up support and market entry assistance.